A spinoff of animated The Loud House, The Casagrandes has a funny, loving & adventurous Mexican-American multi-generational family theme.

Nickelodeon announced that Eugenio Derbez (Overboard, Instructions Not Included) will be the voice of Dr. Santiago, the Casagrandes patriarch. The main crux of the story is the Santiago family: Dr. Santiago, a physician living and working in Peru, and the father of 11-year-old Ronnie Anne, voiced by Izabella Alvarez (Westworld) and Bobby, where Carlos PenaVega (Big Time Rush) lends his voice.

Also part of the main cast are Ken Jeong, who voices Mr. Stanley Chang, a friend, and patient train conductor, and Melissa Joan Hart (Sabrina the Teenage Witch), voicing Mrs. Becca Chang, a quirky, smart and funny zoologist and wife to Stanley.

The Casagrandes features two multi-generational families, the Santiago’s and the Chang’s — two families with active and incredible children. In an exclusive interview with EW, Derbez spoke of his enthusiasm:

“It’s outrageous and funny and has heart. This is what a Latino kid show should look like, big fun and mainstream with some Latin spice. I’m grateful to Nickelodeon for asking me to be a part of it.”

The Casagrandes brings forth many funny and touching stories of the daily life that every kind of family can relate to.

“We’re thrilled to have Eugenio, Melissa, and Ken on board to make these characters as relatable and funny as can be,” said Ramsey Naito, Nickelodeon’s EVP of Animation Production and Development.

Rounding out the cast in this wonderful and diversely cast animation include Leah Lei Gold (Legion) as 12-year-old Sid Chang, Ronnie Anne’s new friend, and Lexi Sexton as Adelaide Chang, Sid’s 6-year-old little sister.

Nickelodeon’s The Casagrandes is set to premiere in October 2019.